David:

Moab from DIA is about 350 miles.  I think you'd end up
spending all your time driving.  I'd suggest exploring
the mtns west of Denver and Fort Collins.

Trail Ridge Road in Rocky Mtn Nat'l Park is supposed to
open May 25th or 26th.  For a while, the cuts through
big snow drifts near the top are amazingly deep.  A
treat to drive early in the season.
http://www.nps.gov/romo/planyourvisit/trail_ridge_road_const.htm

Another idea is to drive the Poudre River Canyon W of
Fort Collins, over Cameron Pass.  Down at the W base is
the "moose visitor center" where moose come to visit....
The chances of seeing a moose around there are pretty
high.

The Peak-to-Peak Highway from Nederland (head of Boulder
Canyon) to Estes Park is a beautiful drive.  It is still
snowing in the high country, so the peaks should be
white.

If you DO head to Moab, and it is daylight when you get
to Utah, don't fail to turn S from I-70 at Cisco and go
down the river road along the Colorado into Moab.

Richard
Boulder